New 129 Nomenclature - revised
JAX® Bulletin Number 1
June 1999; Revised June 2001
A large degree of genetic diversity among 129 substrains was recently identified by scientists at The Jackson Laboratory (Simpson et al., Nat Genetics 16:19-27, 1997), and subsequently by investigators at Case Western Reserve University (Threadgill et al., Mamm Genome 8:390-393, 1997). Because of the importance of 129 mice in creating "knockout" and other targeted mutant mice, the International Committee on Standardized Genetic Nomenclature for Mice introduced a new nomenclature to distinguish different 129 parental lines and related 129 strains.
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